Targeting Purinergic Signaling for Perioperative Organ Protection
نویسندگان
چکیده
منابع مشابه
Targeting purinergic signaling for perioperative organ protection.
1001 May 2013 A D VA N C E M E N T S in the field of anesthesia have led to significant improvements in our monitoring capabilities, safer anesthetic drugs, and improved pain control. Despite this remarkable progress, acute organ injury remains one of the leading causes for morbidity and mortality in surgical patients. Patients who require a major surgical intervention—such as cardiothoracic, v...
متن کاملPerioperative Organ Protection in Cardiac Surgery
Perioperative organ protection refers to the set of strategies to lessen the intensity of the surgical and anesthetic stress. A better understanding of mechanisms involved in tissue hypoperfusion, ischemia-reperfusion phenomena, and the protection triggered by certain anesthetic techniques, drugs and adjuvants have been very useful in perioperative organ protection, especially in patients with ...
متن کاملPerioperative organ injury.
Despite the fact that a surgical procedure may have been performed for the appropriate indication and in a technically perfect manner, patients are threatened by perioperative organ injury. For example, stroke, myocardial infarction, acute respiratory distress syndrome, acute kidney injury, or acute gut injury are among the most common causes for morbidity and mortality in surgical patients. In...
متن کاملPurinergic Signaling in Bone
1 Research Center for Ageing and Osteoporosis, Departments of Diagnostics and Medicine, Copenhagen University Hospital Glostrup, 2600 Glostrup, Denmark 2Department of Morphology, Surgery and Experimental Medicine, Section of General Pathology, University of Ferrara, 44121 Ferrara, Italy 3 Bone Biology Laboratory, Department of Cell and Developmental Biology, University College London, London WC...
متن کاملPerioperative myocardial protection
Myocardial protection refers to all strategies that increase the heart’s ability to withstand ischaemic insult, which together with reperfusion injury are principally responsible for cardiac morbidity and mortality after high-risk surgery. The bloodless and motionless operating conditions required for cardiac surgery is an environment diametrically opposed to the metabolic demands of the heart.
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2013
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e3182874686